Optimal Products for Dermal Longevity
- Chloe Moretz
- Oct 14, 2025
- 3 min read
These creams and serums will maintain your skin's health for years.
Longevity clinics have rapidly acquired popularity recently and continue to proliferate. These clinics, dedicated to prevention rather than treatment, assert that they may decelerate the ageing process with contemporary therapies such as red light therapy, intravenous drips, and cryotherapy. The health and beauty industry's present obsession with longevity extends beyond elaborate procedures, resulting in a proliferation of products aimed at promoting long-term skin health, conveniently packaged for home use. Beauty journalist Olivia Falcon simplifies the overwhelming skincare market by presenting her top 10 products for skin lifespan.
Optimal Products for Skin Longevity
Estée Lauder
Advanced Night Repair Eye Lift and Sculpt, £65
Best For: Avoiding tired eyes

The periorbital skin is seven times more delicate than the facial skin and frequently exhibits the initial indicators of ageing. To prevent the unwelcome remark of ‘you look tired,’ the Lauder team has procured potent peptides – hexapeptide-8 and tripeptide-32 – designed to ameliorate four regions around the eyes: eyelids, inner corners, crow’s feet, and under-eye areas. It is also effective for treating forehead creases and nasolabial folds, rendering the Paris filter on Instagram rather superfluous.
Klira
The Dayscript SPF50, Klira subscription from £59 per month
Best For: Sunscreen that lasts all day

It is widely acknowledged that regular application of SPF is essential, especially on overcast days; yet, attaining the appropriate dosage can be challenging. Dr. Emma Craythorne has developed an innovative solution: a sunscreen that dispenses throughout the day, offering up to eight hours of protection (excluding swimming or sweating). This pioneering sunscreen incorporates various active ingredients and offers four distinct formulations to address certain issues, ranging from sensitivity to hyperpigmentation.
Lab31b
MicroPeptide Needle Power Serum, £83
Best For: Microneedling in a bottle

Appreciate the concept of microneedling yet averse to needles? This is intended for you. Crystallised hyaluronic acid sheets are fragmented into minuscule shards and suspended in a concentrated peptide gel that, when applied to the skin, generates microchannels. The power serum exhibits a slight prickliness upon application, although it effectively administers hyaluronic acid and other active components, including proprietary peptides and bakuchiol, a mild plant-based substitute for retinol.
VOL.U.LIFT
VOL.U.LIFT Skin Rebound Complex, £105
Best For: Ozempic face

As an increasing number of women participate in the Mounjaro movement, weight loss may occur, however skin laxity frequently ensues. Introducing VOL.U.LIFT, a high-performance formulation intended to combat 'Ozempic face.' The foundation is XOSM technology, a patent-pending delivery system that penetrates antioxidants deeply into the skin for enduring restoration. It also contains line-softening bakuchiol, L-ornithine for volume restoration, and HA Silanol, an advanced hyaluronic acid combined with silicium for profound hydration.
Sisley
Sisleÿa L’Integral Anti-Age Longevity Essential Serum, £435
Best For: A post-menopause reset

Following a 2019 study by Stanford University that indicated significant skin alterations occur around the age of 60, experts at Sisley endeavoured to create a solution addressing thinning, dull, and dehydrated skin for this demographic. The serum functions to restore communication among the immunological, vascular, and integumentary systems. A novel ginkgo plant extract fortifies the immune system, while a red algae enhances the appearance of ageing yellowed skin, yielding noticeable effects.
Dr Sebagh
Exo C Booster, £68
Best For: The ultimate skin boost

A novel post-cleanse, pre-serum booster will debut in October, aimed at augmenting your regimen with immediate luminosity and enduring structural restoration. Plant-based exosomes transport Vitamin C and bio-cellular collagen, efficiently delivering essential components to your cells. Clinical research results indicate a 26.7 percent reduction in wrinkles after four weeks, as the serum stimulates endogenous collagen formation.




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